The medical term for the disorder of displaying high platelet count is Thrombocytosis (or thrombocythemia). Platelet counts never stay at one level. Platelets count of a child in the age 6 and 7 years should be between (176-452) to be normal count and exclude thrombotic diseases related to platelets deficiency. Platelet counts decreased by 12% after a 3 -month stay at high altitude and by 31% after a 13-month stay in comparison to sea level counts . Question: What does a platelet count of 450 mean? - Kitchen HIGH PLATELET COUNT. High platelets is a condition in which the blood contains more platelets than normal. The condition needs to be dealt with utmost care and attention . Metabolic syndrome patients are insulin resistant, often hypertensive, and at high cardiovascular disease risk, yet the relationship of platelets to the metabolic syndrome is unknown. Reactive thrombocytosis, also known as secondary thrombocytosis, is the most common cause of elevated platelets. Is 530 a high platelet count? In some cases of thrombocytosis, the platelet count can increase into as high as 750,000 per microliter of blood. If the mean platelet volume is high, it means that your platelet is higher than the average, which means that you are producing too many platelets. •Platelets are responsible for primary hemostasis and wound healing •Normal platelet count is 150,000/μL to 450,000/μL •Bleeding due to thrombocytopenia is typically mucocutaneous •Oral, GI, GU, skin •Moderate-severe bleeding typically occurs with counts <20,000/μL The white population was found to have a higher white blood cell . A 36-year-old member asked: What causes a high platelet count? The first study in patients with ITP used a dose of 0.2-10 µg/kg on days 1 and day 15 . High Platelet Count . Complete Blood Count. Normal Platelet count ↓ Platelet Function : . A slight elevation of the MCH level signifies a higher than usual amount of hemoglobin in the red blood cells. Cancer. It can have many reasons, but two most common are that the cells produce more platelets and that the spleen removes less platelets from the body. I am currently using the following:- Test ace 50mg eod Tren ace 100mg eod Mast p 100mg eod My question is, what could be causing the elevated . Your Platelets value of 432 x10E3/uL is too high. Abstract. Platelet and white blood cell counts are higher among some insulin-resistant patients and may contribute to atherothromboembolic complications. FYI the WHO diagnostic criteria for essential thrombocythemia is platelet count over 450 and a positive test for one of 3 genetic mutations (JAK2, CalR or MPL) and a positive bone marrow biopsy. Certain medicines. If your Platelet count is just slightly above 400k, say 400,005, then this should not be of any concern. The great part is that your levels . This is usually because there's a problem with one of the genes that control the making of platelets. The most common cut off for normal is <450,000/μl. She has been labeled as "failing to thrive."So far, tests haven't come up with anything but a slightly elevated platelet count of 455 (although her pediatrician said that her results were all "normal"). I have had a low grade fever between 99-100.3 degrees since last Dec. every day. Thrombocytes are smaller than red and white blood cells. Here is a list of diseases and disorders which can raise the WBC count of an individual. This can be due to dehydration or an incidental finding. MPNs are very very rare. Some other causes of low platelet counts include: 1. Normal platelet counts are in the range of 150,000 to 400,000 per microliter (or 150 - 400 x 109 per liter), but the normal range for the platelet count varies slightly among different laboratories. A reaction to a disease. Low platelet count is known as thrombocytopenia. Elevated platelet counts are often an incidental or unexpected finding on a complete blood count (CBC . Platelets as a target in inflammation. Causes may include: Iron deficiency. I have had slightly elevated platelets, in the 390 - 440,000 range that we've been following for 10 years with bi annual blood tests. Is a platelet count of 450 high? A combination of baseline borderline iron stores, the reactive response to blood loss and recent surgery can lead to an elevated platelet count that may approach or exceed 1,000,000/µl. Normal platelet counts are in the range of 150,000 to 400,000 per microliter (or 150 - 400 x 109 per liter), but the normal range for the platelet count varies slightly among different laboratories. Too many platelets is called thrombocytosis. An elevated platelet count is known as thrombocytosis. A high platelet count is not considered medically significant until the count is above 450K, normally. A normal platelet count is about 150,000 to 400,000 per milliliter of blood. What causes a platelet count to be slightly elevated? An elevated platelet count is known as thrombocytosis. The Possible Causes of High Platelet Count. People with PV have high red blood cell counts. The highest has been 526,000. Primary thrombocytosis, or essential thrombocythemia, can cause serious bleeding or clotting complications. Case Presentations Patient 1 is an 18-month-old male referred for microcytic anemia 10 days after a tonsillectomy and adenoidectomy. Symptoms of thrombocytopenia A general guide to what you might experience at different platelet counts is: slightly low platelet count (above 50): you will probably have no symptoms at all. It also measures the amount of the iron-rich protein that carries oxygen in red blood cells and the percent of whole blood made up of red blood cells (the hematocrit). Here are some causes of secondary high platelet count: Infection (acute and chronic) Inflammatory disorders (eg Kawasaki's disease) Chronic iron deficiency. As platelets course through the vasculature of inflamed tissue, they are exposed to soluble mediators such as lipid mediators, cytokines and chemokines released by activated leucocytes, ECs and perivascular cells (Fig. For instance: PLT count 400 is high count but still within preset normal levels. On a clinical level, thrombocytosis is classified "mild" at a platelet count between >500,000 μL and <700,000 μL; "m … Red blood cells are one of the major components of blood, along with white blood cells and platelets. If your platelet level is just outside the normal range, then it is probably a meaningless finding that can be followed by future blood counts. 1).These mediators engage with receptors on platelets to elicit an activation response that is characterized by the degranulation of dense . A reaction to a disease. Platelet count. Blood Test Basics. Dizziness or lightheadedness. If you just got over a bad infection, your platelet count will be higher. In looking back at my labs over the last 10 years I've had slightly elevated platelets--somewhere around 25 to 50 points higher than the max normal range. High platelet count: There are many causes for a high platelet count. In a healthy person, there are usually 150,000 to 450,000 platelets per microliter of blood. In most cases, your platelet count will . The majority of people who experience this are asymptomatic but a small group of patients with other risk factors may develop blood clots . Should we delve further into the elevated platelet count or go with the dr. and pass it off as normal? A high platelet count is 400,000 (400 × 10 9 /L) or above. The hemoglobin level dropped slightly after initial hydration, but by day 8, it was 10 g/dL. How high is the highest that platelets can go .some of the nurses that call me back with my platelet count when it's at 500,000 say it's only slightly elevated don't worry but when I see a hematologist they look at you as if it's the end of the world so I get conflicting outcomes Rapid destruction or overuse of platelets (possibly due to infection or autoimmune problems) Excess, or trapped, platelets in the spleen. How high r ur platelets? Slightly high platelet count. The higher end of the normal platelet count range may vary from lab to lab, but is typically around 350 to 450 × 10 9 / L.. Doctors can detect thrombocytosis during routine blood tests. I don't know how serious your condition is, but elevated platelet count can lead to clots when there's no need for them. When it comes to the causes of high platelet count, in some cases it can be some underlying condition, such as inflammation, infection, surgery or injury, or, in the worst cases, this condition can be caused by some disease of the blood or bone marrow, such as anemia or cancer. A reaction to a disease. Treatment for this condition depends on the cause. The two most common causes are a pre-existing condition or a bone marrow abnormality. undefined 21 years experience. Both high platelet counts and low platelet counts can have associated risks that can range from either not causing any noticeable health problems to being very serious and life-threatening. What causes high platelet count? Mild to moderately elevated platelet counts are commonly seen when chronic inflammation is present. Platelets come from the same blood-forming cells that make other blood cells. You received your blood test result with a Platelets value of 432 x10E3/uL. A normal platelet count ranges from 150,000 to 450,000 platelets per microliter of blood. Low platelet count is what would be associated with abnormal bleeding, and that would also be exacerbated by taking aspirin or blood thinners. When it is caused by something else, it's secondary, or reactive, which is most likely the case. The ideal platelet range is 150,000 to 400,000 per mcL in most healthy people. Sometimes blood-forming cells just make too many platelets. Yes: Any inflammatory condition can cause reactive increase in platelet count but to only a certain extent. Health care providers typically use a test known as a complete blood count (CBC) to measure the number of red and white blood cells and platelets within a particular blood sample. People with thrombocytosis often don't have signs or symptoms. Seven of 12 patients at 3, 6 or 10 µg/kg achieved a platelet count of greater than 50 × 10 9 /l. Thrombocytosis is the medical term used to describe the display of elevated platelet count. I have become aware of joint pain (all of my joints) over the last year; the pain has become constant over the last six . Platelets come from the same blood-forming cells that make other blood cells. High MPV/normal platelet count - It occurs in people with chronic myelogenous leukemia (cancer) and hyperthyroidism. Hematology and Oncology 30 years experience. This test measures the number of red blood cells, white blood cells and platelets in a sample of blood. His platelet count steadily increased to 500,000/L by day 6 and 812,000/L by day 8. People with thrombocytosis often don't have signs or symptoms. Could endometriosis cause a slightly elevated platelet count? However, some studies . Even though the platelet count is elevated for a short time (or even indefinitely after splenectomy), secondary thrombocytosis does not typically lead to abnormal blood clotting. A high platelet count can be identified through routine blood tests. Elevated platelets in a person's blood work may indicate reactive thrombocytosis. In most cases, your platelet count will . After certain infections, major surgery or trauma. Slightly elevated white blood cell count usually indicates an infection, a problem in the immune system or bone marrow, or it can be a side-effect of a drug. Answer. Blood is a fairly complex substance that requires a pretty strict . I've just had a call from my doctor requesting a repeat blood test due to a slightly elevated platelet count. A high platelet count is called thrombocytosis. People with essential thrombocythemia might have signs and symptoms related to blood clots and bleeding, including: Headache. It may indicate a recent history of bleeding (unlikely with your dog's normal history) and very rarely is an indicator of a particular type of bone marrow disease called Megakaryocytic Leukemia. I had a platelet function test with normal results this year, but my internist would like me to see a hematologist for the first time, the appointment is in 3 weeks. A slightly elevated level of MCV on a CBC signifies macrocytic anemia, a diagnosis of abnormally large blood cells. Elevated White Blood Cell Counts Should Be Monitored Since white blood cells help fight disease, viruses, and infections, you may assume that an elevated white blood cell count is a good thing. Dr. Keith Stockerl-Goldstein answered. Platelets 0 x10E3/uL 0 1,000. High platelet counts can lead to stroke, heart attack, or a blood clot in a vein. High platelet count is known as thrombocytosis. In healthy pediatric subjects normal count platelet ranges between 250,000 μL and 450,000 μL. There are several conditions that could cause an elevated platelet count such as anemia. Overview: Thrombocytosis, also called thrombocythemia, is generally defined as a platelet count greater than a defined upper limit of normal that may vary between 350,000/μl to 600,000/μl, depending on the laboratory or medical reference. 150,000-450,000. low platelet level (thrombocytopenia) less than 150,000. My potassium levels are also very slightly high, but I have been supplementing with 200mg potassium daily so this may be the culprit for that. As a matter of fact, counts change almost daily. In both children and adults, infections are the most common cause of an elevated platelet count. The platelet count is marginally on the higher side. A variety of medications have the ability to thin your blood and lower the count of blood-clotting platelets. Readings of the mean corpuscle hemoglobin, MCH, within the range of 27 to 31 picograms per cell are considered normal. The nurse practitioner at the hematology office stated I have no reason to be concerned, as these are very minor elevations and my white count is usually normal (occasionally slightly elevated). An elevated platelet count greater than 2 SD defines a condition of thrombocytosis. 4.8k views Answered >2 years ago. A good Platelets is usually between 140 and 415 x10E3/uL. An elevated platelet count is known as thrombocytosis. A high platelet count is called thrombocytosis. This is because slightly elevated platelet counts rarely cause any major problems, and they have many causes. The clinical features can relate to an increased incidence of arterial . This is usually because there's a problem with one of the genes that control the making of platelets. A peripheral smear revealed an increased number of platelets but no morphologic abnormalities. Is 490 a high platelet count? Recent blood work showed slightly elevated platelets at 427. Signs and symptoms of reactive thrombocytosis, if they do occur, relate to the underlying condition. People with essential thrombocythemia might have signs and symptoms related to blood clots and bleeding, including: Headache. Blood platelet counts at the higher end of normal suggest a high risk of cancer in men aged 60 or over, and should be investigated, according to new University of Exeter research. You need to have your platelet count anywhere between 150,000 and 450,000/mcL, but certain health conditions can push your platelet count up, which can cause serious complications. Medication. I have 3 different solid cancers as well as Chronic Lymphocytic Leukaemia (CLL) so my WBC count is a bit higher at 150 and my Platelets range between 150 to 200. Having elevated platelet counts can be associated with cancer, with one study reporting that about 11% of men with high platelets and about 6% of women with high platelets had cancer. As long as you are within the accepted range—150,000 to 400,000 (or a little more; like I said 425,000 is still normal). That is a very wide range. Treatment Reactive thrombocytosis. Question: My daughter is one year old and only weighs 13.5 lbs. No specific complaints had prompted her visit—it was for a routine examination, blood . Do you mean platelets were only 1,400 or 1.4 million. Of interest, at one visit, my iron had improved, yet my platelets increased from the previous visit, when my iron had been lower. Your platelet count is not very high - just slightly above the "normal" level. Normally WBC range should be between 4 to 11 and platelets 150 to 400. Created with Raphaël 2.1.4. Dizziness or lightheadedness. Within a few weeks of iron supplementation, their platelet counts rose to elevated values before normalizing, coincident with recovery of the hemoglobin concentration. My counts were consistently high for years (never had a normal CBC) and I wasn't diagnosed until my platelets hit a million. Certain types of leukemia (cancer of blood forming tissues), for example, Acute Lymphocytic . Signs and symptoms of reactive thrombocytosis, if they do occur, relate to the underlying condition. Sadly, this isn't the case as it means that your white blood cells are engaging in a battle that you may be unaware of and the body feels seriously . Normal Platelet Count for teenager 14 years must be a value from 176 to 452 to be considered healthy. low platelet count (30 to 50): you might bruise more easily and bleed for longer if you cut yourself.  This elevation can be extreme, with platelet counts greater than 1 million cells per microliter. The platelet count remains elevated at 625,000/ml. Sometimes blood-forming cells just make too many platelets. I have had chronic pain (approximately 3 years) in my neck and shoulders. Normal platelet counts are in the range of 150,000 to 400,000 per microliter (or 150 - 400 x 109 per liter), but the normal range for the platelet count varies slightly among different laboratories. Though these may seem like significant numbers, it is important to remember that the majority of elevated platelet counts are caused by a reactive process, such . Normal platelet counts are in the range of 150,000 to 400,000 per microliter (or 150 - 400 x 109 per liter), but the normal range for the platelet count varies slightly among different laboratories. Sometimes blood-forming cells just make too many platelets. I, too have elevated platelet counts. Many times it is reactive--in response to another medical issue like an infection or having no splee. If you've had something like a stroke or other clotting issue, they'll take that into account. Mild to moderately elevated platelet counts are commonly seen when chronic inflammation is present. There are numerous causes of thrombocytosis and fortunately, the majority are benign and transient. 5) Autoimmune Disorders Autoimmune disorders can impair bone marrow function, decrease platelet production, or increase the destruction of platelets [ 18 , 19 , 20 ]. A bone marrow aspirate and biopsy are performed and reveal a normocellular marrow. A high platelet count can be caused by: A problem with blood-forming cells. I also show hi-normal neutrophils in many of my labs, or there's a higher number of neutrophils but no lab range. Those receiving romiplostim by single IV injection at 10 µg/kg showed elevated platelet counts at over 1000 × 10 9 /l. The problem. If you are concerned, I would ask your dr. about your count being slightly elevated. Moderately high platelet counts such as yours sometimes means that another inflammatory disease or infection is ongoing. Red blood cells help carry oxygen throughout the body. Thrombocytosis is treated with medications that inhibit platelet production in bone marrow. 3. Thrombocytosis is an increase in platelets more than 500 x 10 9 /L, commonly found incidentally in a routine blood test. Increased platelet counts (thrombocytosis) are rarely cause for any concern, especially if the rest of the complete blood count is normal. A photomicrograph of the peripheral blood film is shown. Take care, Michelle in CA Hence, your doctor is right in wanting to repeat the tests and monitor the progress. The red blood cell (RBC) count, white blood cell (WBC) count, and mean corpuscular volume (MCV) were normal. The platelet count is used to diagnose disease and to help determine the cause of excess bleeding or clotting. Dr. RAJESH Sehgal answered. My DR. says not to worry that it is low enough and it is common to test outside of the normal range. A high platelet count can be caused by: A problem with blood-forming cells. Moderately high platelet counts such as yours sometimes means that another inflammatory disease or infection is ongoing. On day 5, an iron tablet was prescribed. In a normal CBC, the Platelet Count can range from 130k to 400K. Upon review of her medical record, her platelet count had been slightly but consistently elevated (450 to 525 × 10 3 /µL) for at least 2 years. Our health systems are a little different but our health problems are exactly the same. Normal platelet counts are in the range of 150,000 to 400,000 per microliter (or 150 - 400 x 109 per liter), but the normal range for the platelet count varies slightly among different laboratories. After your next blood test, your doctor may advise a "watch and see" - just regular blood testing to keep an eye on things. This is usually because there's a problem with one of the genes that control the making of platelets. This analysis helps you to check if your Platelets value is within normal range. (5, 6, and 7) MPV blood test high. Platelets not only prevent bleeding injuries but they also promote proper blood circulation in the body. It means your body is making too many platelets. A higher-than-normal number of platelets is called thrombocytosis. high platelet level (thrombocytosis) more than 450,000. normal platelet level. If you've had significant blood loss from a recent surgery or an injury, your elevated platelet count might resolve on its own. If it remains persistently high or show a rising trend, then it can be an inflammatory condition like rheumatoid arthritis. Any amount above 450,000 is considered a high platelet count. Thrombocytosis describes an elevated platelet count above 400,000 per ml. Treatment Reactive thrombocytosis. 2. If you've had significant blood loss from a recent surgery or an injury, your elevated platelet count might resolve on its own. There are broadly two types of thrombocytosis: Primary haematological disease: Essential thrombocythaemia (also referred to as primary thrombocytosis). In general, a platelet count more than 450,000 cells per microliter is considered elevated; this is known as thrombocytosis. Platelets . A high platelet count can be caused by: A problem with blood-forming cells. platelet counts • If platelets are low secondary to bone-marrow failure usually there will be a hemostatic defect • Template bleeding time if properly performed can assess in vivo platelet effectiveness - Thrombocytosis, if secondary to myeloproliferative disorder • Post-splenectomy thrombocytosis usually not a problem Answer (1 of 3): Platelet counts of 425,000 and 380,000 are normal counts. Second opinion] I had elevated platelet count of 447 in November got referred to a hematologist and my blood work came back normal but i had elevated total protein and ALT, calcium was on the normal b . If you have a chronic infection or an inflammatory disease, your platelet count likely will remain high until the condition is under control. If you have a chronic infection or an inflammatory disease, your platelet count likely will remain high until the condition is under control. Treatment for this condition depends on the cause. Doctors measure your red blood cell count to help diagnose medical conditions and learn more about your health. What is high red blood cell count? This is because slightly elevated platelet counts rarely cause any major problems, and they have many causes. Determine the platelet count at which patients exceed a 3% risk of cancer We will do this by examining electronic medical records of patients with a platelet count in the normal range, and cancer registry records. Elevated platelets, also called thrombocytosis is a relatively common finding. Explore which cancers patients with high-normal counts are most at risk of, and the cancer staging at diagnosis. 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